In fast-growing microorganisms. a tRNA concentration profile enriched in major isoacceptors selects for the biased usage of cognate codons. This optimizes translational rate for the least mass invested in the translational apparatus. Such translational streamlining is thought to be growth-regulated. https://www.nacrack.com/quick-sale-Graffiti-Chicago-Refection-Skyline-Canvas-super-sale/