Esophageal Disorders including noncardiac chest pain, swallowing Conditions, and regurgitation/rumination syndromes are common in scientific practice. Virtually all gastroenterologists and medical professionals handling these Conditions present empiric and symptomatic treatment method with no an assessment or understanding of the cause of the signs. In a review in this challenge of https://www.directivepublications.org/journal-of-gastroenterology-hepatology-and-endoscopy-research/